"Food for Thought: NIA’s Mark P. Mattson on Neurodegeneration"

(Excerpt from Science Watch^®, September/October 2003, Vol. 14, No. 5)
The death of the neuron is the ultimate act of pathology in a litany of devastating brain disorders from Alzheimer’s and Huntington’s disease to Parkinson’s and stroke. Each of these conditions has its own trigger for neuronal degeneration—whether oxygen starvation, amyloid-beta peptide aggregation, or genetic malfunction—but the biochemical cascades and signaling mechanisms that succumb on the route from cell dysfunction to cell death may be common to all. As a result, unraveling the genetic, cellular, and biochemical factors involved in the life and death of brain neurons has turned out to be one of the hottest research areas in neuroscience
[read complete interview]

See also another feature with Mattson; "Mark P. Mattson answers a few questions about this month's fast breaking paper in the field of Neuroscience & Behavior."

View the record of Mark P. Mattson in ISIHighlyCited.com.

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